Anthony Hopkins - Old Ptolemy
David Bedella - Scribe
Jessie Kamm - Child Alexander
Angelina Jolie - Olympias
Val Kilmer - Philip
Fiona O'Shaughnessy - Nurse
Connor Paolo - Young Alexander
Patrick Carroll - Young Hephaistion
Brian Blessed - Wrestling Trainer
Peter Williamson - Young Nearchus
Morgan Christopher Ferris - Young Cassander
Robert Earley - Young Ptolemy
Aleczander Gordon - Young Perdiccas
Christopher Plummer - Aristotle
Gary Stretch - Cleitus
John Kavanagh - Parmenion
Nick Dunning - Attalus
Marie Meyer - Eurydice
Mick Lally - Horse Seller
Colin Farrell - Alexander
Jared Leto - Hephaistion
Elliot Cowan - Ptolemy
Joseph Morgan - Philotas
Ian Beattie - Antigonus
Jonathan Rhys-Meyers - Cassander
Denis Conway - Nearchus
Neil Jackson - Perdiccas
Garrett Lombard - Leonnatus
Chris Aberdein - Polyperchon
Rory McCann - Crateros
Michael Dixon - Campfire Soldier
Tim Pigott-Smith - Omen Reader
Raz Degan - Darius
Erol Sander - Persian Prince
Stéphane Ferrara - Bactrian Commander
Tadhg Murphy - Dying Soldier
Jean Le Duc - Fat Eunuch
Francisco Bosch - Bagoas
Annelise Hesme - Stateira
Tsouli Mohammed - Persian Chamberlain
Toby Kebbell - Pausanius
Laird Macintosh - Greek Officer
Rosario Dawson - Roxane
Rab Affleck - Attalus' Henchman
Féodor Atkine - Roxane's Father
Harry Kent - Cup Bearer #1
Sam Green - Cup Bearer #2
Bin Bunluerit - Indian King
Jaran Ngamdee - Indian Prince
Brian McGrath - Doctor
Suzanne Bullock - Roxane dancer
Kate Elouise - Roxane dancer
Gillian Grueber - Roxane dancer
Michelle Lukes - Roxane dancer
Anjali Mehra - Roxane dancer
Anthony Jean Marie Kurt - Bagoas dancer
Marta Barahona - Bagoas dancer
Monica Zamora - Bagoas dancer
Benny Maslov - Bagoas dancer
Tania Matos - Bagoas dancer
Leighton Morrison - Bagoas dancer
Isaac Mullins - Bagoas dancer
Monica Perego - Bagoas dancer
Matthew Powell - Bagoas dancer
rest of cast listed alphabetically:
Benjamín Benítez - Amato
Max Bollinger - Young Greek Official
Charles Haigh - Aristander
Peter Rnic - Greek Nobleman
Greg Orvis - Celtic Diplomat (uncredited)
