Keke Palmer - Akeelah
Laurence Fishburne - Dr. Larabee
Angela Bassett - Tanya
Curtis Armstrong - Mr. Welch
J.R. Villarreal - Javier
Sean Michael - Dylan
Sahara Garey - Georgia
Lee Thompson Young - Devon
Jumper Lark - Young Reporter
Julito McCullum - Terrence
Erica Hubbard - Kiana
Eddie Steeples - Derrick-T
Dalia Phillips - Ms. Cross
Tzi Ma - Mr. Chiu
Jeris Poindexter - Steve
Sara Niemietz - Polly
George Hornedo - Roman
Craig Wasson - Ted Saunders
Katie Kerwin McCrimmon - Herself
Marjorie Harris - National Spelling Bee Head Judge
Jacques Bailly - National Spelling Bee Pronouncer
Krysten Leigh Jones - Tough Girl #1
Amirah Hawkins - Tough Girl #2
Jeff Marlow - District Judge
Chloe Conroy - District Pronouncer
Lee Garlington - Regional Judge
Sidney Ganis - Regional Pronouncer
Austin Herrera Davis - Cheating Boy
Janet Borrus - Cheating Boy's Mom
Wolfgang Bodison - Akeelah's Father
Marcus Hawkins Dungey - Chuckie
Bonita Friedericy - Volunteer
Caroline J. Smith - Mary Calveretti
Neil Soni - Rajeev Subramonian
Jack Ong - Korean Grocer
Lauren Sanchez - Reporter
Fay Hauser - Woman on TV
Keshell Lucas - Little Girl on TV
Corina Boettger - Red-Haired Girl
Shyann Chatman - Eighth-Grade Girl
Todd Wagner - Regional Bee Assistant Judge
Brittany Curran - District Speller #1
Alexandra Rieger - District Speller #2
Eric Don - Skinny Speller
Julia Kelleher - Regional Speller #2
Zac Gardner - Regional Speller #3
John A. Ausick - "Sacciform" Speller
Maddy Kloss - "Scutellate" Speller
Mason Green - "Longicollis" Speller
Jessy J. Hwang - "Ginglymus" Speller
Biplab Panda - "Empennage" Speller
Alexander Christian Stephans - "Souchong" Speller
Katie L. Brown - "Intussusception" Speller
John Oxenreiter - "Engastrimythic" Speller
Katie Olson - "Escharotic" Speller
Jason Ortenberg - "Flocculation" Speller
Lance Norling - Boy in Wheelchair
Jmeka Cherrel - Driver
Kahlil Ashanti - Postman
Courtney Taylor Burness - Additional (voice)
D.T. Carney
Andrea Frisby - Audience Member
Stephanie Hass - National Spelling Bee Press Reporter (unconfirmed)
Lanaria Johnson - Audience Member
Kelron Mixon - Audience member
Justin D. Reininga - Spelling Bee Audience Member
Holly Traister - Finals Judge
Brittany M. Wildman - Speller
Rennie Cowan - Parent (uncredited)
Eric Fallecker - Student (uncredited)
Dava Hulsey - Finals - Judge (uncredited)
Kaitlyn Williams - Featured Speller (uncredited)
