Jim Moret - Newscaster
Stuart Luce - Irving Steinbloom
Mary Gross - Ma Klapper
Marty Belafsky - Ramblin' Sandy Pitnik
Michael Baser - Pa Klapper
Jared Nelson Smith - Young Chuck Wiseman
Ryan Raddatz - Bill Weyburn
Todd Lieberman - Fred Knox
Matthew Joy - Boy Klapper
Laura Harris - Girl Klapper
Brian Riley - Young George Menschell
Harry Shearer - Mark Shubb
Michael McKean - Jerry Palter
Christopher Guest - Alan Barrows
Eugene Levy - Mitch Cohen
Catherine O'Hara - Mickey Crabbe
Bob Balaban - Jonathan Steinbloom
Rachael Harris - Steinbloom's Assistant
Tyler Forsberg - Young Jonathan Steinbloom
Paul Dooley - George Menschell
Jim Ortlieb - David Kantor
Andrew Dickler - 1971 Dell Wiseman
Thomas Lowry - 1971 Howard Wiseman (as Thom Lowry)
Keva Rosenfeld - 1971 Chuck Wiseman
Brian Allen - 1960s Mitch & Mickey Bass
Danny Merritt - 1960s Mitch & Mickey Guitar
Paul Benedict - Martin Berg
Floyd Van Buskirk - Steve Lang (as Floyd Vanbuskirk)
Jane Lynch - Laurie Bohner
John Michael Higgins - Terry Bohner
Parker Posey - Sissy Knox
Christopher Moynihan - Sean Halloran
David Blasucci - Tony Pollono
Patrick Sauber - Jerald Smithers
Steve Pandis - Johnny Athenakis
Mark Nonisa - Mike Maryama
Cameron Sprague - Young Terry Bohner
LeShay N. Tomlinson - Steinbloom's Secretary (as Leshay Tomlinson)
Mina Kolb - Dr. Mildred Wickes
Jim Piddock - Leonard Crabbe
Don Lake - Elliott Steinbloom
Deborah Theaker - Naomi Steinbloom
Fred Willard - Mike LaFontaine
Ed Begley Jr. - Lars Olfen
Wendel Meldrum - Witch #1
Diane Delano - Witch #2
Jim Jennewein - Witch #3 (as James Jennewein)
Richard Hicks - Witch #4
Michael Hitchcock - Lawrence E. Turpin
Larry Miller - Wally Fenton
Jennifer Coolidge - Amber Cole
Michael Mantell - Deputy Mayor
Bill Cobbs - Blues Musician
Freda Foh Shen - Melinda Barrows
Darlene Kardon - Shirley Steinbloom
Scott Williamson - PBN TV Director
Joe Godfrey - Mitch & Mickey Bass
Bruce Gaitsch - Mitch & Mickey Guitar
Diane Baker - Supreme Folk Defense Lawyer
